Views: 1 Author: Site Editor Publish Time: 2026-03-05 Origin: Site
Sulforaphane: Regulating DHT Levels, Awakening Hair Regeneration Vitality
Sulforaphane (SFN), as a highly promising active ingredient, has garnered significant attention due to its multiple physiological activities. Widely found in cruciferous vegetables such as broccoli and radish, this compound has been proven to possess powerful antioxidant and anti-inflammatory properties, regulate cellular metabolism and signal transduction. More importantly, recent research has gradually revealed its positive impact on hair growth.
The Most Common Type of Hair Loss — Androgenetic Alopecia (AGA)
Hair growth is regulated by multiple factors including genetics, hormones, and environment, among which androgens serve as the core regulatory factor. They maintain the orderly cycle of "anagen-catagen-telogen" phases by acting on hair follicle cells. Once androgen regulation becomes abnormal and the hair growth cycle is disrupted, hair loss may occur [1].
Androgenetic alopecia (AGA) shows significant gender differences in incidence rates in China, with men reaching 21.3% and women 6.0% [2]. The core pathogenic mechanism of AGA is closely related to abnormal hormone regulation, and dihydrotestosterone (DHT) plays a key role in this mechanism.
Dihydrotestosterone: The Core "Pathogenic Factor" in Androgenetic Alopecia
Dihydrotestosterone (DHT) plays an important role in androgenetic alopecia (AGA). Under the action of 5α-reductase, androgens are converted into dihydrotestosterone (DHT). This substance attacks hair follicles in specific areas, leading to shortened anagen phase, prolonged telogen phase, and gradual miniaturization (normal hair is replaced by fine vellus hair), eventually causing complete dormancy and cessation of hair production [2].
Pioneer Herb — Broccoli Series Extracts
Sulforaphane (SFN) generally exists in cruciferous vegetables in the form of its precursor glucoraphanin (GLR). Glucoraphanin is a naturally occurring "glucosinolate" compound in cruciferous vegetables with long-lasting antioxidant effects. It is degraded into sulforaphane (SFN) through intestinal flora or myrosinase.
Huahan Bio — Deeply engaged in the R&D and production of broccoli series extracts GLR+® and BrocPio+®, launches four categories of multi-specification products:
Product Category | Specification Details | Product Features |
Broccoli Seed Aqueous Extract GLR® | Glucoraphanin 13%~20% | Excellent flavor, high solubility and clarity |
Broccoli Seed Aqueous Extract Composite Solid Beverage GLR® | Conversion rate 80% | High conversion rate, excellent stability |
Sulforaphane Broc Pio® | 1%, 10%, 95%, with customized specifications available | Fast absorption, high activity |
Stabilized Sulforaphane Broc Pio® | Sulforaphane 1%, 10% | Room temperature storage, excellent stability |
【Product Features】
Proprietary varieties | Proprietary base | 650 pesticide residues not detected | Low heavy metals
【Core Product Advantages】
> Excellent stability for long-term activity protection: Relying on advanced production processes and quality control technology, we effectively maintain the structural stability of core components such as glucoraphanin and sulforaphane, reducing activity loss during storage and processing.
> High conversion rate + high bioavailability: Through process optimization, we significantly improve the conversion of glucoraphanin to active sulforaphane, enhancing the human body's absorption and utilization efficiency of sulforaphane.
> Solving "safety anxiety": Products pass "650 pesticide residue screenings + heavy metal special testing," achieving zero pesticide residue detection, with heavy metal content far below national and industry safety standards.
> Overcoming "application challenges": Featuring high solubility and clarity, the solution is transparent and precipitate-free after water dissolution, suitable for liquid products such as beverages and oral liquids. It has excellent flavor without bitter or astringent taste, meeting consumer demand for "additive-free" products.
> Controllable source, stable quality: Relying on Huahan Bio's self-developed superior broccoli varieties and standardized proprietary planting bases, we achieve full-process control. Combined with a full-chain quality system, we ensure stable and consistent characteristics and active ingredient content in every batch of raw materials.
【Diverse Application Scenarios】
> Functional foods: solid beverages, gel candies, pressed candies, chocolate, etc.
> Health products: tablets, hard capsules, soft capsules, liquid beverages, etc.
> Special dietary foods, etc.
Choosing Pioneer Herb means not only selecting a "high-quality, high-stability" raw material but also choosing a "from-source-to-terminal" quality assurance system. With an extremely rigorous attitude, we will escort your product R&D, giving you more confidence in market promotion!
⭐ If you have raw material needs, sample trials, or technical consultation, please feel free to contact us~
Yasmine | International sales Dept
T +86 21 3462 5090
C +86 13524715503
Office: Rm 502, Bldg 8, # 518 Xinzhuan Rd, Songjiang Dist., Shanghai, China
Factory: No.1 Yangtang Ave., Ganzhou High-tech Zone, Ganxian Dist., Ganzhou, Jiangxi, China
References：
[1] 房子鑫,陈虎.雄激素调控下的毛发生长周期及其与脱发的关系[C]//中国智慧工程研究会.2025信息化背景下的健康管理经验交流会论文集.河北中医药大学;河北中医药大学第四附属医院;,2025:616-618.DOI:10.26914/c.cnkihy.2025.065215.
[2] 宋雪妍.脱发不可怕！科学应对雄激素性脱发[J].药物与人,2025,(12):88-89.
[3] 吴庭辉.探究雄激素对烧烫伤小鼠愈合过程中毛发及毛囊干细胞增殖的影响[D].塔里木大学,2020.
[4] Naito A, Sato T, Matsumoto T, Takeyama K, Yoshino T, Kato S, Ohdera M. Dihydrotestosterone inhibits murine hair growth via the androgen receptor. Br J Dermatol. 2008 Aug;159(2):300-5. doi: 10.1111/j.1365-2133.2008.08671.x. Epub 2008 Jun 28. PMID: 18547308.
[5] Sasaki M, Shinozaki S, Shimokado K. Sulforaphane promotes murine hair growth by accelerating the degradation of dihydrotestosterone. Biochem Biophys Res Commun. 2016 Mar 25;472(1):250-4. doi: 10.1016/j.bbrc.2016.02.099. Epub 2016 Feb 26. PMID: 26923074.
[6] Petkovic M, Leal EC, Alves I, Bose C, Palade PT, Singh P, Awasthi S, Børsheim E, Dalgaard LT, Singh SP, Carvalho E. Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway. J Nutr Biochem. 2021 Dec;98:108817. doi: 10.1016/j.jnutbio.2021.108817. Epub 2021 Jul 14. PMID: 34271100; PMCID: PMC10580548.
